气道炎症和气道重塑(Airway remodelling)是支气管哮喘(以下简称哮喘)的两个主要病理学特征。目前对哮喘的认识及其治疗策略以针对慢性非特异性气道炎症为主。虽然哮喘气道重塑已得到关注,其发生机制的研究也已开始,但确切机制尚未明确。许多研究表明,信号转导通路通过调节炎症 Airway inflammation and airway remodeling are two major pathological features of bronchial asthma (hereinafter referred to as asthma). The current understanding of asthma and its treatment strategies for chronic non-specific airway inflammation based. Although asthma airway remodeling has received attention, the mechanism of its research has begun, but the exact mechanism is not yet clear. Many studies show that signal transduction pathways regulate inflammation