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以黑暗链霉菌Streptomycetenebrarius163为出发菌株,应用磁场、磁场复合吖啶橙、耐受氨甲酰妥布霉素、磁场复合耐受氨甲酰妥布霉素筛选得到5株高产菌株,经摇瓶发酵复筛后表明,其总效价与氨甲酰妥布霉素均比出发菌株提高了25%以上
The strain Streptomycetenebrarius163 was used as a starting strain. Five strains of high-yielding strains were screened by magnetic field, magnetic acridine orange, resistant to carbamoyl-tobramycin and magnetic field resistant carbamoyl-tobramycin. After fermenting the bottle, it showed that its total potency and carbamoyl-tobramycin increased more than 25%