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建立了高效毛细管电泳系统分析法，分析体液样品中２９种ＣＮＳ药物，作为ＣＮＳ药物中毒的快速的初筛方法。血、尿样品用有机溶剂萃取，胃液直接进样。用酸、弱碱和中性３组缓冲液体系进行电泳分离。以组分与电渗流迁移时间之比的相对迁移时间和紫外吸收光谱为定性指标。最低检测浓度０５～５μｇ·ｍｌ－１。在此法基础上可增加分析品种。通用的提取方法可避免漏检，广谱分离条件便于分类，专一分离条件便于定性。本法用于实际中毒样品分析，证实所建方法操作简便、分析时间短、杂质干扰小。
A high performance capillary electrophoresis system analysis method was established to analyze 29 CNS drugs in bodily fluid samples as a rapid initial screening method for CNS drug poisoning. Blood, urine samples with organic solvent extraction, gastric juice directly into the sample. Acid, weak base and neutral 3 buffer system electrophoresis separation. The relative migration time and ultraviolet absorption spectra of the ratio of component to electroosmotic flow migration time were used as qualitative indexes. The lowest detection concentration of 0 5 ~ 5μg · ml-1. On the basis of this law can increase the variety of analysis. Universal extraction method to avoid missed inspection, broad spectrum separation conditions easy to classify, separate conditions to facilitate qualitative. This method is used for the analysis of the actual poisoning samples, confirming the method is easy to operate, the analysis time is short, the impurity interference is small.