将人鼻咽癌上皮型细胞(CNE)与小鼠的器官块接触后,以小鼠肾包膜将其包裹一起进行培养。不同时间后取器官块进行光镜、透射和扫描电镜检查。结果发现,肾包膜包裹可使分散的癌细胞形成癌巢,内有大量核分裂相,并向器官内部侵袭。经一段时间后,器官细胞虽有不同程度的变性和坏死,但癌细胞的存活和生长仍良好,并见核分裂相,说明癌细胞尚在繁殖。扫描电镜下可见癌细胞有丝状伪足和微绒毛与器官细胞紧密接合和沟通。 Human nasopharyngeal epithelial cells (CNE) were brought into contact with the organ fragments of mice, and then they were co-cultured with the mouse renal capsule. After different time, the organ was taken for light microscopy, transmission and scanning electron microscopy. The results showed that the renal capsule can make the spread of scattered cancer cells formed cancer nests, there are a large number of nuclear fission and invasion of the internal organs. After a period of time, although there are varying degrees of organ cell degeneration and necrosis, but the survival and growth of cancer cells is still good, and see the mitotic phase, indicating that cancer cells are still breeding. Scanning electron microscopy showed cancer cells with filopodia and microvilli and organ cells in close contact and communication.