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目的对奥美拉唑与胶体果胶铋治疗反流性食管炎(RE)的临床效果进行对比分析。方法选取我院2012年3月~2014年3月收治的120例反流性食管炎患者，通过随机数字表法分为甲组(n=60)和乙组(n=60)，甲组患者给予奥美拉唑治疗，乙组患者采用胶体果胶铋治疗，观察和比较两组患者临床治疗效果。结果甲组患者治疗总有效率90.00%，显著高于乙组78.33%，差异显著(>0.05)；甲组患者不良反应发生率6.67%低于乙组15.00%，但两组患者不良反应发生率比较差异无统计学意义(>0.05)。结论在反流性食管炎治疗过程中，奥美拉唑与胶体果胶铋均能实现不错的临床效果，但奥美拉唑临床疗效相对优于胶体果胶铋，值得临床推广应用。“,”Objective To analyze the clinical comparative ef ects of reflux esophagitis cured by omeprazole and col oidal bismuth pectin.Methods 120 patients who suf ered from the reflux esophagitis and who accepted treatments in our hospital from March, 2012 to March, 2014 were taken as the research objects, and these patients were used random number table method randomly divided into the group A (n=60) and group B (n=60). In the A group, they were treated with the omeprazole while in the B group, they were treated with the col oidal bismuth pectin.Then, the curing ef ects of these two groups of patients were compared and obseved. Results The response rate in the A group was 90.00%, which was evidently higher than that in the B group was 78.33%, and the dif erences was significant ( >0.05); In addition, the adverse reaction rate in the A group was 6.67% ,which was lower than that of B group was 15%, but two patients with adverse reaction rate had no significant dif erence ( >0.05).Conclusion In the course of reflux esophagitis treatment,omeprazole and col oidal bismuth pectin also can achieve good clinical ef ect, but the clinical ef ects of omeprazole is bet er than col oidal bismuth pectin,thus should be promoted in the clinical application.