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目的探讨孤立性纤维性肿瘤的临床与病理特征、诊断及治疗。方法对妇科临床诊治的1例盆腔腹膜后孤立性纤维性肿瘤进行病理组织学观察和免疫组化检测,并复习相关文献。结果该例盆腔腹膜后孤立性纤维性肿瘤系因“无症状盆腔肿物”而就诊,病理表现为肿瘤细胞由梭形细胞构成,与嗜酸性胶原混杂排列,肿瘤中血管较丰富,并可形成典型的“血管外皮瘤样”区;免疫组化:CD34(+++),Bcl-2(++),CD99(++),Ki-67(约1%+)。结论盆腔腹膜后孤立性纤维性肿瘤为中间型肿瘤,临床上较罕见,术前难以通过影像学检查鉴别,确诊需依靠病理检查,临床上多呈良性经过,局部完整切除后很少复发,但需长期随访。
Objective To investigate the clinical and pathological features, diagnosis and treatment of solitary fibrous tumor. Methods One case of pelvic retroperitoneal solitary fibrous tumor diagnosed by gynecology was observed by histopathology and immunohistochemistry, and the related literatures were reviewed. Results The pelvic retroperitoneal solitary fibrous tumor was treated by “asymptomatic pelvic mass”. The pathological manifestations were that the tumor cells were composed of spindle cells, mixed with eosinophilic collagen, and the vessels in the tumor were relatively abundant A typical “hemangioperitoid” region can be formed; immunohistochemistry: CD34 (+++), Bcl-2 (++), CD99 (++), Ki-67 (about 1% +). Conclusions Pelvic peritoneal solitary fibrous tumor is an intermediate tumor, which is rare in clinic. It is difficult to be identified by imaging before operation. Diagnosis depends on pathological examination. Most of patients with benign and recurrent pelvic peritoneum rarely recur after complete and partial resection Need long-term follow-up.