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目的 观察益气养血活血中药对实验性血虚证大鼠视网膜病理改变的影响。方法 将 70只Wistar大鼠随机分为正常组、对照组、大剂量给药组、小剂量给药组和预防组。除正常组外 ,其它 4组用乙酰苯肼造成血虚证模型。各血虚组大鼠治疗 2 0d、40d后分别每组随机取 7只鼠的视网膜进行光镜观察 ,40d每组随机取 2只眼视网膜作电镜观察。结果 预防组大鼠视网膜未发现病理改变 ;中药治疗组视网膜病理损害程度轻于对照组 ;其中大剂量组治疗 40d检查的结果更为明显。结论 益气养血活血中药对早中期视网膜病变具有较好的防治作用
Objective To observe the effect of Yiqi Yangxue Huoxue Chinese medicine on pathological changes of retina of experimental blood deficiency rats. Methods 70 Wistar rats were randomly divided into normal group, control group, large dose group, low dose group and preventive group. In addition to the normal group, the other four groups used acetophenone to cause a blood deficiency syndrome model. After 30 days and 40 days of treatment, the retinas of 7 rats in each group were randomly observed by light microscopy. After 40 days, the retinas of 2 eyes in each group were randomly taken for electron microscopy. Results No pathological changes were found in the retina of the preventive group. The degree of pathological damage of the retina in the Chinese medicine treatment group was lighter than that of the control group, and the results of the 40 days examination in the high-dose group were more obvious. Conclusion Yiqi Yangxue Huoxue Chinese medicine has a good preventive and therapeutic effect on early and mid-term retinopathy