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目的 通过探讨特发性肺纤维化 (IPF)的临床特点 ,提高对 IPF的认识。方法 对 10例符合“中华医学会呼吸分会特性肺纤维化诊断标准”的 IPF患者进行回顾性分析。结果 男女之比 3∶ 7,年龄 34～ 70岁 ,平均 5 5 .8岁。 10例均有咳嗽伴进行性呼吸困难和 Velcro罗音。 X线表现为磨玻璃样、网状、结节状、条索状及蜂窝状阴影。 10例均有弥散功能障碍 ,3例限制性通气功能障碍 ,3例混合性通气功能障碍。动脉血气分析示低氧血症。结论 对长期咳嗽伴有呼吸困难的患者 ,及时行胸部 X线、肺功能、动脉血气分析及支气管肺泡灌洗检查 ,能对本病做出正确的诊断
Objective To explore the clinical features of idiopathic pulmonary fibrosis (IPF) to improve the understanding of IPF. Methods Ten cases of IPF patients who met the diagnostic criteria of pulmonary fibrosis in Respiratory Branch of Chinese Medical Association were retrospectively analyzed. Results The ratio of men and women 3: 7, aged 34 to 70 years, mean 55.8 years. All 10 patients had cough with progressive dyspnea and Velcro rales. X-ray showed glassy, reticular, nodular, cord-like and honeycomb shadows. Ten patients had diffuse dysfunction, three patients with restrictive ventilatory dysfunction and three patients with mixed ventilatory dysfunction. Arterial blood gas analysis showed hypoxemia. Conclusion In patients with long-term cough with dyspnea, prompt chest X-ray, pulmonary function, arterial blood gas analysis and bronchoalveolar lavage examination can make a correct diagnosis of the disease