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目的:探讨异烟肼联合阿米卡星支气管镜下注药治疗疑似耐多药肺结核的临床效果。方法:此次依不同治疗方式将2015年1月-2017年1月于我院诊治的疑似耐多药肺结核患者60例分组为:对照组用莫西沙星治疗,观察组用异烟肼+阿米卡星支气管镜下注药治疗;记录两组患者各项实验数据,将所获相关数据作对比分析,探讨了异烟肼联合阿米卡星支气管镜下注药治疗疑似耐多药肺结核效果。结果:观察组(异烟肼+阿米卡星支气管镜下注药)治疗疑似耐多药肺结核的效果优于对照组(莫西沙星)治疗效果,组间比较差异有统计学意义(P<0.05)。结论:疑似耐多药肺结核患者用异烟肼+阿米卡星支气管镜下注药治疗效果佳,可有效改善患者临床症状,值得临床上广泛应用。
Objective: To investigate the clinical efficacy of isoniazid combined with amikacin bronchoscopy in the treatment of suspected multi-drug resistant pulmonary tuberculosis. Methods: According to the different treatment methods, 60 suspected MDR-TB patients diagnosed and treated in our hospital from January 2015 to January 2017 were grouped as follows: the control group was treated with moxifloxacin, the observation group was treated with isoniazid + A Mika star bronchoscopy under the injection of drugs; record the two groups of patients with experimental data, the data obtained for comparative analysis of isoniazid in combination with amikacin bronchoscopy to treat suspected MDR-TB effect . Results: The treatment group (isoniazid + amikacys bronchoscopy) had better effect on the treatment of suspected MDR-TB compared with the control group (moxifloxacin), the difference was statistically significant (P < 0.05). Conclusion: The treatment of suspected MDR-TB patients with isoniazid and amikacin bronchoscopic injection is effective, which can effectively improve the clinical symptoms of patients, it is worth widely clinical application.