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综述了环糊精(包括α-环糊精,β-环糊精和γ-环糊精)衍生物在金属催化有机合成中的应用,主要包括其作为金属离子配体、金属纳米粒子稳定剂和反相相转移催化剂在氧化、水解、还原、偶联等金属催化反应中的应用.其中环糊精衍生物作为金属离子配体应用最广,由于环糊精部分与底物形成包结络合物,拉近了底物和具有催化活性的金属离子的距离,并固定了底物的反应部位,往往可以显著提高催化反应的反应速率,增强反应的区域选择性和对映选择性.
The applications of cyclodextrins (including α-cyclodextrin, β-cyclodextrin and γ-cyclodextrin) derivatives in metal-catalyzed organic synthesis are reviewed, including their applications as metal ion ligands, metal nanoparticle stabilizers And reverse phase transfer catalyst in the oxidation, hydrolysis, reduction, coupling and other metal catalytic reactions.Which cyclodextrin derivatives as the metal ion ligand is the most widely used, due to part of the cyclodextrin and the substrate to form a network The close distance between the substrate and the catalytically active metal ions and the immobilization of the reaction sites of the substrate can often significantly improve the reaction rate of the catalytic reaction and enhance the regioselectivity and enantioselectivity of the reaction.