耳硬化症有明显的家族性发病倾向,有报道常染色体显性遗传出现率为25～40％。各种遗传标记曾被用于证明耳硬化症的遗传学基础。近来正在寻找白细胞抗原与耳硬化症的关系。作者以74例(女50,男24)手术证实为耳硬化症的病人为样本,进行A和B位点白细胞抗原的组织分型。白细胞A和B抗原用Umta大 Ear sclerosis has a clear tendency of familial onset, there are reports of autosomal dominant genetic incidence of 25 to 40%. Various genetic markers have been used to demonstrate the genetic basis of otosclerosis. Recently, we are looking for the relationship between leukocyte antigen and otosclerosis. The authors used 74 patients (female 50, male 24) confirmed as otosclerosis patients as samples, the A and B site leukocyte antigen tissue typing. Leukocyte A and B antigens are large with Umta