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哮喘或者慢性阻塞性肺疾病(COPD)患者的炎症性肠病(IBD)发病率显著增加,该研究结果发表于《European Respiratory Journal》期刊上。IBD和气道疾病可能与常见的炎症通路、遗传和环境因素相关联。肠道和呼吸道上皮有共同的胚胎起源,类似的解剖结构,而且都是人体和环境之间的屏障器官。由环境因素引发的免疫功能障碍是IBD和如哮喘和COPD等气管疾病共同的发病机理。哮喘女性患者比男性患者更容易患克罗恩病,而男性COPD患者比女性患者更容易患溃疡性结肠炎,这类研究结果若在未来得到确认,可能对炎症性肠病早期发现,和患者的治疗管理有重要意义。(源自:药品资讯网)
The incidence of inflammatory bowel disease (IBD) is significantly increased in patients with asthma or chronic obstructive pulmonary disease (COPD), the results of which are published in the European Respiratory Journal. IBD and airway disease may be linked to common inflammatory pathways, genetic and environmental factors. The gut and the respiratory epithelium have a common embryonic origin, a similar anatomical structure, and are all barrier organs between the human body and the environment. Immune dysfunction caused by environmental factors is a common pathogenesis of IBD and tracheal diseases such as asthma and COPD. Women with asthma are more susceptible to Crohn’s disease than men, whereas men with COPD are more likely to develop ulcerative colitis than women. Confirmation of such studies in the future may lead to early detection of inflammatory bowel disease and to patient The treatment management is of great importance. (From: Drug Information Network)