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肥胖与增加心血管疾病的危险有联系。虽然知道白色脂肪组织(white adipose tissue,WAT)产生大量炎症和致动脉粥样硬化的细胞因子和趋化物,但在动脉粥样硬化中脂肪源性趋化信号对慢性炎症的影响尚不清楚。组织学检查发现,血管周围WAT紧靠血管壁,尤其是那些有发生动脉粥样硬化趋?
Obesity is linked to increased risk of cardiovascular disease. Although white adipose tissue (WAT) is known to produce a large number of inflammatory and atherogenic cytokines and chemotaxis, the effect of adipogenic chemotactic signals on chronic inflammation in atherosclerosis is unclear. Histological examination found that WAT close to the vessel wall, especially those with atherosclerosis tend to occur?