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应用免疫组化ABC法对80例食管癌进行胃泌素(Gastrin,GT)标记,结果GT阳性29例(36.3%)。研究证明:低分化鳞癌和未分化癌GT阳性率较高,GT阳性肿瘤易发生淋巴结转移。研究了GT阳性病例与其生物学行为之间的关系,并对产生GT的肿瘤细胞来源进行了探讨。
80 cases of esophageal cancer were labeled with gastrin (GT) by immunohistochemical ABC method. Results showed that 29 cases (36.3%) were positive for GT. Studies have shown that the positive rate of GT is higher in poorly differentiated squamous cell carcinoma and undifferentiated carcinoma, and lymph node metastasis is more likely to occur in GT-positive tumors. The relationship between GT positive cases and their biological behaviors was studied, and the origin of tumor cells producing GT was discussed.