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目的:观察当归六黄汤联合西药治疗阴虚火旺型肺结核的临床疗效。方法:将60例阴虚火旺型肺结核患者随机分为对照组(30例)和治疗组(30例)两组,两组均接受2HRZE/4HR化疗方案治疗,治疗组加用自拟加味当归六黄汤,观察两组治疗前后痰菌(痰涂片)、肺部结核灶(X线胸片)、肝功能损害和临床证候的变化。结果:经治疗后,治疗组总有效率为89.3%(治愈9例,显效8例,有效8例,无效3例),对照组总有效率为64.3%(治愈5例,显效7例,有效6例,无效10例),治疗组疗效显著优于对照组(P<0.05);治疗组治疗后痰菌转阴率,肺部结核灶吸收明显提高,咳嗽或咳痰、咯血或痰中带血丝、五心烦热或潮热盗汗等临床症候显著改善,肝损伤发生率降低,且明显优于对照组(P<0.05)。结论:当归六黄汤联合西药可显著改善阴虚火旺型肺结核临床症状,明显提高疗效。
Objective: To observe the clinical effect of Angelica Liuhuang Decoction combined with western medicine in treating Yin-Huo-wang-type pulmonary tuberculosis. Methods: Sixty cases of Yin-Huo-Huo-wang tuberculosis patients were randomly divided into control group (30 cases) and treatment group (30 cases). Both groups were treated with 2HRZE / 4HR chemotherapy. Huang Tang, observed before and after treatment of sputum bacteria (sputum smear), pulmonary tuberculosis (chest X-ray), liver dysfunction and clinical syndrome changes. Results: After treatment, the total effective rate of the treatment group was 89.3% (cured in 9 cases, markedly effective in 8 cases, effective in 8 cases and ineffective in 3 cases). The total effective rate in the control group was 64.3% (5 cases were cured and 7 cases markedly effective) 6 cases, and 10 cases were ineffective). The curative effect of the treatment group was significantly better than that of the control group (P <0.05). The sputum negative rate, the absorption of pulmonary tuberculosis in the treatment group were significantly increased, the cough or sputum, hemoptysis or sputum Blood stasis, five upset or hot flashes night sweats and other clinical symptoms significantly improved, the incidence of liver injury decreased, and significantly better than the control group (P <0.05). Conclusion: Angelica Liuhuang Decoction combined with western medicine can significantly improve the clinical symptoms of Yin-Huo-wang-type pulmonary tuberculosis, and obviously improve the curative effect.