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目的:以冠状动脉造影(CAG)为金标准,评价腺苷负荷超声心动图(ASE)试验诊断冠心病(CHD)的敏感性和特异性。方法:40例临床疑诊CHD患者,分别静脉注射腺苷(140μg·kg-1.min-1)6min(总剂量为0.8mg/kg)。出现节段性室壁运动异常为阳性。所有患者1周内行CAG检查。结果:ASE诊断CHD的敏感性为82.6%,特异性为88.2%,准确性为85.0%;诊断单支、双支和3支冠状动脉病变的敏感性分别为75.0%,85.7%,100%,且不良反应少。结论:ASE诊断CHD安全可靠。
OBJECTIVE: To evaluate the sensitivity and specificity of coronary artery angiography (CAG) as a gold standard in the diagnosis of coronary heart disease (CHD) by adenosine stress echocardiography (ASE). Methods: Forty patients with clinically suspected CHD were treated with intravenous adenosine (140μg · kg-1.min-1) for 6 minutes (the total dose was 0.8mg / kg). Occurrence of segmental wall motion abnormalities were positive. All patients underwent CAG examination within 1 week. Results: The sensitivity, specificity and accuracy of ASE in diagnosing CHD were 82.6%, 88.2% and 85.0%, respectively. The sensitivity of ASE in diagnosing CHD was 75.0%, 85.7% and 100% respectively, And adverse reactions less. Conclusion: ASE diagnosis of CHD safe and reliable.