目的了解新兵人群W135群流脑IgG抗体的流行分布情况,为今后预防工作提供科学依据。方法运用血清流行病学调查方法,采用酶联免疫吸附试验(ELISA)技术,对北京军区空军近4年来自7个省市的360名新兵血清进行了W135群流脑IgG抗体检测,统计分析其阳性率。结果发现各年间新兵血清W135群流脑IgG抗体差异有统计学意义,不同省市阳性率为37.04%～64.44%,平均为50.83%;抗体含量为0.00～100.31μg/ml,平均(3.96±7.44)μg/ml;地区间差异有统计学意义,浙江省(64.44%)、内蒙古(62.75%)和陕西省(57.50%)较高,河南省(37.04%)和北京市(40.00%)较低;入伍前工作与否,其抗体阳性检出率有差异,但没有统计学意义;差别的主要原因可能与各地区隐性感染和时间长短有关。结论入伍新兵人群W135群流脑IgG抗体阳性率地区差异显著。新兵入伍期间,应采取预防接种、健康教育等措施来预防流行性脑脊髓炎的流行。 Objective To understand the epidemiological distribution of IgG antibodies in W135 group of recruits and to provide a scientific basis for future prevention. Methods Serum epidemiological investigation method was used to detect the IgG of W135 group by 360 serogroups of recruits from 360 provinces and cities of Beijing Military Region Air Force for the past 4 years by enzyme-linked immunosorbent assay (ELISA) Positive rate. The results showed that there was a significant difference in the IgG antibody of W135 group among recruits in each year, the positive rate was 37.04% -64.44% in different provinces, with an average of 50.83%; the antibody content was 0.00-100.31μg / ml, mean (3.96 ± 7.44 ) μg / ml. There were significant differences among different regions in Zhejiang Province (64.44%), Inner Mongolia (62.75%) and Shaanxi Province (57.50%), Henan Province (37.04%) and Beijing ; Before working or not, the detection rate of antibody positive is different, but there is no statistical significance; the main reason for the difference may be related to the latent infection and the length of time in each region. Conclusion The positive rate of IgG antibodies in W135 group recruits from recruits is significantly different among the recruits. Recruits during the recruitment should take vaccination, health education and other measures to prevent the epidemic of encephalomyelitis.