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目的探讨阴道镜下子宫颈不典型转变区的远期演变规律。方法回顾总结本院防癌专科门诊阴道镜检查诊断为子宫颈不典型转变区患者的远期随论资料。984例患者分成治疗组(A组)和观察组(B组),A组498例经物理方法治疗,B组486例未经治疗,均定期随诊3~5年,观察两组子宫颈不典型转变区的转归。结果A组中371例(74.50%)病变保持痊愈状态,119例(23.90%)病变较前消退,5例病变保持不变,3例进展,无一例癌变。B组中38例(7.82%)病变自然痊愈,292例(60.08%)病变自然消退,134例(27.57%)病变保持不变,19例病变进展,3例发展为癌。两组病变转归的差异有显著的统计学意义(P<0.01)。结论阴道镜下子宫颈呈不典型转变区的患者应积极治疗和长期随访。阴道镜是随访子宫颈病变的可靠工具之一。
Objective To explore the long-term evolution of cervical atypical transitional area under colposcopy. Methods The retrospective summary of our hospital anti-cancer specialist outpatient colposcopy diagnosis of cervical dysplasia in patients with long-term follow-up data. 984 patients were divided into treatment group (A group) and observation group (B group). A group of 498 cases were treated by physical methods, B group 486 cases were untreated, were regularly followed up for 3 to 5 years. The typical transition area of the outcome. Results A total of 371 cases (74.50%) of the patients in group A were cured. 119 cases (23.90%) of the lesions had subsided earlier, 5 cases remained unchanged, 3 cases progressed, and none had carcinogenesis. In group B, 38 cases (7.82%) recovered spontaneously, 292 cases (60.08%) naturally regressed, 134 cases (27.57%) remained unchanged, 19 cases progressed and 3 cases developed carcinoma . The difference between the two groups was statistically significant (P <0.01). Conclusion Colposcopic cervical atypical transitional area should be actively treated and long-term follow-up. Colposcopy is one of the reliable tools for follow-up of cervical lesions.