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目的探讨米索前列醇不同给药方式对剖宫产产后出血的影响。方法回顾性分析2011年11月-2012年11月在我院住院分娩的168例剖宫产产妇的临床资料,观察直肠给药(直肠组)与口服给药(口服组)产妇产后出血量及不良反应情况。结果直肠组产妇产后2h出血量明显低于口服组(P<0.05);两组产妇产后24h出血量比较无显著差异(P>0.05);两组产妇产后出血发生率比较无显著差异(P>0.05);口服组不良反应发生率明显高于直肠组(P<0.05)。结论米索前列醇治疗剖宫产产后出血安全、有效,经直肠给药疗效更佳。
Objective To investigate the effects of misoprostol on the postpartum hemorrhage after cesarean section. Methods The clinical data of 168 cases of cesarean delivery in hospital from November 2011 to November 2012 were retrospectively analyzed. The amount of postpartum hemorrhage and the number of postpartum hemorrhage in rectum group and oral group (oral group) Adverse reactions. Results The amount of bleeding in the rectum group was significantly lower than that in the oral group at 2 hours (P <0.05). There was no significant difference in the amount of hemorrhage between the two groups (P> 0.05). There was no significant difference in the incidence of postpartum hemorrhage among the two groups (P> 0.05). The incidence of adverse reactions in oral group was significantly higher than that in rectal group (P <0.05). Conclusion Misoprostol is safe and effective in treating cesarean section postpartum hemorrhage, and has better efficacy after rectal administration.