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目的:观察阿奇霉素治疗小儿社区获得性肺炎的临床疗效并对阿奇霉素的可靠性进行评估。方法:将2013年3月到2014年3月被诊断为社区获得性肺炎的小儿168例,随机分为两组,观察组84例,对照组84例。对照组给予常规的治疗:多休息,多饮水,补充大量的维C,静滴头孢哌酮钠舒巴坦钠40~80mg(kg·d),等分2~4次滴注,用药3天。观察组给予同对照组一样的治疗,并在此基础上,给予静滴阿奇霉素10mg(kg·d),每日一次,用药3天。结果:治疗3天后,观察两组小儿的情况,对照组总有效率77.4%,不良反应的发生率3.6%;观察组总有效率92.9%,不良反应的发生率1.2%。结论:阿奇霉素治疗小儿社区获得性肺炎的临床疗效较其他类的抗生素如头孢菌素类好,并且可靠性高,因此在临床上可使用阿奇霉素治疗小儿社区获得性肺炎。
Objective: To observe the clinical efficacy of azithromycin in children with community-acquired pneumonia and to evaluate the reliability of azithromycin. Methods: A total of 168 children diagnosed with community-acquired pneumonia from March 2013 to March 2014 were randomly divided into two groups: observation group (84 cases) and control group (84 cases). Control group given conventional treatment: rest, drink plenty of water, add a lot of Victoria C, intravenous cefoperazone sodium and sulbactam sodium 40 ~ 80mg (kg · d), equally divided 2 to 4 times instillation, medication for 3 days. The observation group was given the same treatment as the control group, and on this basis, intravenous azithromycin 10 mg (kg · d) was given once daily for 3 days. Results: After 3 days of treatment, the two groups of children were observed. The total effective rate was 77.4% in the control group and 3.6% in the adverse reaction group. The total effective rate in the observation group was 92.9% and the incidence of adverse reactions was 1.2%. Conclusion: The azithromycin in children with community-acquired pneumonia clinical efficacy than other antibiotics such as cephalosporins, and high reliability, so the clinical use of azithromycin can be used to treat pediatric community-acquired pneumonia.