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目的:术前应用髂内动脉灌注化疗,同时行血管栓塞疗法的介入治疗,以提高中晚期宫颈癌的手术切除率。方法:治疗组24例,应用诺维本、阿霉素、顺铂行介入治疗,3周~4周插管1次,3次为一疗程,与对照组22例行静脉用药相比较。结果:治疗组总有效率为70.8%,有51.2%的患者经介入治疗后手术切除;对照组总有效率31.8%,仅有13.6%的患者进行了手术切除,治疗组疗效明显优于对照组(P<0.01)。结论:中晚期宫颈癌的术前介入治疗,安全有效,能缩小原发病灶,提高局部治疗效果,预防周围淋巴结和脏器转移,提高手术切除率。
Objective: Preoperative application of internal iliac artery infusion chemotherapy, while interventional therapy of vascular embolization in order to improve the rate of surgical resection of cervical cancer. Methods: In the treatment group, 24 cases were treated with noviben, doxorubicin and cisplatin, intubated once every 3 weeks to 4 weeks, 3 times as a course of treatment, compared with 22 cases in the control group. Results: The total effective rate was 70.8% in the treatment group and 51.2% in the control group. The total effective rate was 31.8% in the control group and 13.6% in the control group. The curative effect in the treatment group was significantly better than that in the control group (P <0.01). Conclusion: The preoperative interventional treatment of advanced cervical cancer is safe and effective, which can reduce the primary lesion, improve the local therapeutic effect, prevent the peripheral lymph nodes and organs from metastasis, and improve the surgical resection rate.