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目的:探讨饮食控制对交界性糖耐量异常(BGGI)孕妇不良妊娠结局及新生儿出生Aparg评分及体重的影响。方法:对2012~2013年在医院产检的孕妇行糖耐量筛查中符合BGGI诊断标准孕妇124例随机分饮食干预组及非干预组各62例,随访并记录两组新生儿及不良妊娠结局情况。结果:干预组分娩时空腹血糖(FPG)、餐后2 h血糖(2hFPG)、糖化血糖蛋白(HbA1c)水平显著低于非干预组分娩时,差异有统计学意义(P<0.05)。干预组巨大儿发生率、产后出血率、剖宫产率及孕妇体重增长显著低于非干预组(P<0.05),而两组胎膜早破、妊娠期高血压疾病、难产率差异无统计学意义(P>0.05)。干预组新生儿宫内窘迫、窒息、胎儿生长受限发生率低于非干预组,差异有统计学意义(P<0.05),而两组新生儿低血糖、新生儿黄疸、死胎发生率差异无统计学意义(P>0.05)。结论:饮食干预能有效改善BGGI孕妇血糖代谢状况,降低剖宫产率及母婴相关并发症,有利于母婴预后。
Objective: To investigate the effect of dietary control on adverse pregnancy outcomes in pregnant women with borderline impaired glucose tolerance (BGGI) and neonatal Aparg score and body weight. Methods: 124 pregnant women with BGGI diagnostic criteria for screening of pregnant women in the hospital during 2012 ~ 2013 were randomly divided into two groups: dietary intervention group (n = 62) and non-intervention group (n = 62) .All the newborns and adverse pregnancy outcomes . Results: The levels of fasting blood glucose (FPG), 2h postprandial blood glucose (2hFPG) and glycosylated glycoprotein (HbA1c) in the intervention group were significantly lower than those at the non-intervention group (P <0.05). The incidence of macrosomia, postpartum hemorrhage, cesarean section rate and weight gain of pregnant women in intervention group were significantly lower than those in non-intervention group (P <0.05). There was no statistical difference between the two groups in premature rupture of membranes, pregnancy-induced hypertension Significance (P> 0.05). The incidence of neonatal intrauterine distress, asphyxia and fetal growth restriction in the intervention group was significantly lower than that in the non-intervention group (P <0.05), while there was no significant difference in neonatal hypoglycemia, neonatal jaundice and stillbirth Statistical significance (P> 0.05). Conclusion: Diet intervention can effectively improve blood glucose and glucose metabolism in pregnant women with BGGI, reduce the rate of cesarean section and maternal-infant related complications, which is in favor of maternal and infant prognosis.