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西咪替丁是组胺H_2-受体拮抗剂,有较强的抑制胃酸分泌作用,广泛用于胃酸分泌增多性疾病和上消化道出血的治疗。除临床最常用于十二指肠溃疡和治疗返流性食管炎外,在临床上还有多方面的药理作用,故在应用范围日趋广泛。 1.用于前列腺增生症的治疗。前列腺增生症是前列腺上皮的过度增生,该上皮是特异地受双氢睾丸酮的影响,西咪替丁使双氢睾丸酮减少,抑制了前列腺上皮的异常增生,并使已增大的上皮失去双氢睾丸酮的作用而萎缩,使前列腺变软,有人治疗17例,除3例因故未继续治疗外,14例症状明显好转。
Cimetidine is a histamine H 2 -receptor antagonist, has a strong inhibitory effect on gastric acid secretion, is widely used in the treatment of gastric acid secretion increased disease and upper gastrointestinal bleeding. In addition to the clinical most commonly used in the treatment of duodenal ulcer and reflux esophagitis, there are many in the clinical pharmacological effects, it is increasingly widespread in the scope of application. 1. For the treatment of benign prostatic hyperplasia. Prostatic hyperplasia is an overgrowth of the prostate epithelium that is specifically affected by dihydrotestosterone, diminished by dihydrotestosterone, inhibition of prostatic epithelial dysplasia, and loss of enlarged hydrogenated epithelium The role of testosterone and atrophy, so that the prostate becomes soft, 17 cases were treated, with the exception of 3 cases did not continue treatment, the symptoms were significantly improved in 14 cases.