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《维妮好一推得》是以卫生棉条做载体,由苦参、蛇床子、土茯苓、川椒、榆皮、土槿皮等中药和壬苯醇醚-9(NP-9)复方配制的药液组成的妇科消毒药剂。本实验采用改良Sander-Cramer方法评价其体外杀精作用。采用雌性实验家兔,分自然对照组、生理盐水对照组、NP-9对照组及《维妮好一推得》高剂量组和低剂量组,阴道给药,进行组织学炎症刺激程度的判定。结果表明《维妮好一推得》的体外杀精作用是单用NP-9的10倍;载体和药液共同留置阴道在试验应用剂量下对阴道无明显刺激作用,评分在可接受范围内。
“Vini good push” is made of tampon carrier, from Sophora, Cnidium, Smilax, Chuan Jiao, Yu skin, hibiscus skin and other Chinese medicine and nonoxynol-9 (NP-9) Preparation of the liquid composition of gynecological disinfectant. In this experiment, Sander-Cramer method was used to evaluate the in vitro spermicidal effect. Female rabbits were divided into natural control group, normal saline control group, NP-9 control group and “Vini-push” high-dose group and low-dose group, vaginal administration, to determine the degree of inflammation of tissue inflammation . The results showed that “Vitini good push” in vitro spermicidal effect is NP-9 alone 10 times; vector and liquid together vaginal vaginal administration in the test dose did not significantly stimulate the vagina, the score was within acceptable range .