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目的观察不同放疗方案对肺癌脑转移瘤患者预后的影响。方法选取医院收治的肺癌脑转移瘤患者213例,随机分为观察组107例和对照组106例。观察组采取同期推量放射治疗方案,对照组采取全脑照射+三维适形放射治疗方案。观察2组的临床效果,住院时间和中位生存期。结果观察组总有效率为96.26%,高于对照组的78.30%(P<0.05),观察组的住院时间短于对照组,中位生存期长于对照组,差异均显著(P<0.05)。结论同期推量放射治疗方案用于肺癌脑转移瘤患者的临床效果显著,值得临床推广应用。
Objective To observe the effects of different radiotherapy regimens on the prognosis of patients with brain metastases of lung cancer. Methods Totally 213 patients with brain metastases of lung cancer who were admitted to hospital were randomly divided into observation group (107 cases) and control group (106 cases). Observation group to take the same dose of radiation therapy program, the control group to take whole brain irradiation + three-dimensional conformal radiotherapy program. The clinical effects, hospital stay and median survival of the two groups were observed. Results The total effective rate in the observation group was 96.26%, which was significantly higher than that in the control group (78.30%, P <0.05). The length of stay in the observation group was shorter than that in the control group and the median survival time was longer than that in the control group (P <0.05). Conclusions The same period of the dose of radiation therapy for patients with brain metastases of lung cancer clinical effect is significant, worthy of clinical application.