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用组织化学的方法研究ＢＡＬＢ／ｃ小鼠胚胎（１４ｄ）至成年十二指肠的发育分化过程。结果显示：（１）胚胎１４～１７ｄ，上皮细胞内富含ＲＮＡ，胚胎１９ｄ，ＲＮＡ含量减少。生后１周末时，ＲＮＡ含量增加，２周末接近成年。（２）胚胎ｌ５ｄ，上皮细胞内可见糖原，１６ｄ时，糖原略增多，１７ｄ时，糖原消失。胚胎１５～１７ｄ，上皮表面糖蛋白逐渐增多，提示纹状缘表面细胞衣正在形成，（３）胚胎１７６时，Ｇ－６－Ｐａｓｅ出现，此后，酶活性渐增强，生后４周末基本达到成年水平。
The development and differentiation of BALB / c mouse embryos (14d) to adult duodenum were studied histochemically. The results showed that: (1) embryos 14 ~ 17d, the epithelial cells are rich in RNA, embryonic 19d, RNA content decreased. At the end of one week after birth, the RNA content increased and approached the age of 2 weeks. (2) embryo l5d, glycogen within the epithelial cells can be seen, 16d, slightly increased glycogen, 17d, glycogen disappeared. From 15 to 17 days after embryo implantation, glycoproteins gradually increased on the surface of the epithelium, suggesting that the cell surface coating on the margins of the striatum was forming. (3) G-6-Pase appeared at embryo 176 hours, and then the enzyme activity gradually increased. At 4 weeks after birth, Level.