论文部分内容阅读
本文报道１６１例消化道癌症患者尿多胺的含量分析结果，尿多胺含量比正常人明显增高，比正常均值增高的倍数各为：腐胺０．８６～２．２８倍，精脒０．１１～０．７２倍，精胺２．７６～５．１７倍。本组患者一项多胺增高者占总例数的８８．０％～１００．０％，两项多胺增高者占总例数的６０．８７％～８０．００％。另外，在滤纸电泳图谱的腐胺和精脒色带之间又发现一分离清晰的新色带，在本组患者尿中亦见增高，为正常均值的１．０２～１．４８倍，增高的出现率为４７．０６％～６０．４２％。曾对２１例经手术和２例经化疗的患者进行复查，其各种尿多胺均于治疗后下降，表明尿多胺含量分析可做为消化道癌症患者辅助诊断和估计疗效的参考。
This article reported 161 cases of urinary polyamine content in patients with digestive tract cancer, urinary polyamine content was significantly higher than normal, the multiples higher than the normal mean were: putrescine 0.86 ~ 2.28 times, fine 脒 0. 11 to 0.72 times, spermine 2.76 to 5.17 times. In this group of patients, an increase in polyamines accounted for 88.0% to 100.0% of the total number of cases, and two polyamine elevations accounted for 60.87% to 80.00% of the total cases. In addition, a clear and distinct new ribbon was found between the putrescine and spermidine ribbons of the filter paper electrophoresis pattern, which was also increased in the urine of this group of patients, which was 1.02 to 1.48 times higher than the normal mean value. The occurrence rate was 47.06% to 60.42%. Twenty-one patients undergoing surgery and 2 patients undergoing chemotherapy have been reviewed. Various urinary polyamines have declined after treatment, indicating that urinary polyamine content analysis can serve as a reference for assisted diagnosis and estimation of curative effect in patients with digestive tract cancer.