,SynBioEcoli: a comprehensive metabolism network of engineered E.coli in three dimensional visualiza

来源 :定量生物学(英文版) | 被引量 : 0次 | 上传用户:harryleexxx
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background:A comprehensive metabolism network of engineered E.coli is very important in systems biology and metabolomics studies.Many tools focus on two-dimensional space to display pathways in metabolic network.However,the usage of three-dimensional visualization may help to understand better the intricate topology of metabolic and regulatory networks.Methods:We manually curated large amount of experimental data (including pathways,reactions and metabolites) from literature related with different types of engineered E.coil and then utilized a novel technology of three dimensional visualization to develop a comprehensive metabolic network named SynBioEcoli.Results:SynBioEoli contains 740 biosynthetic pathways,3,889 metabolic reactions,2,255 chemical compounds manually curated from about 11,000 metabolism publications related with different types of engineered E.coli.Furthermore,SynBioEcoli integrates with various informatics techniques.Conclusions:SynBioEcoli could be regarded as a comprehensive knowledgebase of engineered E.coli and represents the next generation cellular metabolism network visualization technology.It could be accessed via web browsers (such as Google Chrome) supporting WebGL,at http://www.rxnfinder.org/synbioecoli/.
其他文献
本文通过对荣华二采区10
“12358”价格举报电话作为价格举报工作的重要窗口,是政府价格主管部门联系人民群众的桥梁和纽带。国家发展改革委拟在全国建成国家、省、市、县四级联网的“12358”价格举
Background:The antineoplastic activity of Chelidonium majus has been reported,but its mechanism of action (MoA) is unsuspected.The emerging theory of systems ph
中国汽车汽配用品行业联合会、中国汽车配件用品市场协会、国家汽车零部件质量监督检验中心、中国汽车工业配件销售公司联合主办,全国发行。《中国汽配市场》中国汽车汽配用
中作321是中国农科院作物所以白金×科情3号为母本、[(台中39×水源300粒)×白金3×I R 24为父本杂交,于1983年育成,1989年在天津市通过审定。一、特征特性:全生育期165天左
水稻(Oryza sativa L.)是世界上重要的粮食作物,随着粮食需求不断增加和耕地面积的持续减少,如何提高水稻的产量已成为育种家和栽培家们最主要的议题。近年来,关于水稻高产的“
扬辐糯1号系用30kRγ射线照射 IR_(29)干种子选育而成,它具有高产、优质、早熟、多抗等特性,属早熟中籼糯品种,比目前当地推广品种增产5—10%,为优质糕点的上等原料。 Yangf
In this paper, we study the energy decay estimates for an Euler-Bemoulli beam with a tip mass, which is clamped at one end and attached a tip mass to the free e