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目的分析脓毒症患者病原菌分布情况及耐药性。方法对2015年1月至2016年1月期间收治的88例脓毒症患者的临床资料进行回顾性分析,总结其细菌培养结果及药敏试验结果。结果本次研究的88例脓毒症患者共分离出病原菌128株,其中革兰阴性菌72株,所占比例为56.25%(72/128);革兰阳性菌42株,所占比例为32.81%(42/128),真菌14株,所占比例为10.94%(14/128)。药敏试验结果显示,多数革兰阴性菌、革兰阳性菌均对临床常用抗菌有广泛耐药性,且呈现出多药耐药性特征。结论脓毒症患者病原菌多存在耐药性,临床需要根据药敏试验选择恰当抗菌药物,保证抗菌药物使用的科学性及合理性。
Objective To analyze the distribution of pathogens in patients with sepsis and drug resistance. Methods Clinical data of 88 patients with sepsis admitted from January 2015 to January 2016 were analyzed retrospectively. The results of bacterial culture and drug sensitivity test were summarized. Results A total of 128 pathogens were isolated from 88 sepsis patients in this study, of which 72 strains were Gram-negative bacteria, accounting for 56.25% (72/128); 42 Gram-positive bacteria, accounting for 32.81 % (42/128), 14 fungi, accounting for 10.94% (14/128). Drug sensitivity test results show that the majority of Gram-negative bacteria, Gram-positive bacteria are widely used in clinical antibacterial resistance, and showed multi-drug resistance characteristics. Conclusion There are many pathogens in patients with sepsis drug resistance, the clinical need to select the appropriate antimicrobial susceptibility testing based on drugs to ensure the scientific use of antibacterial drugs and rationality.