目的：探讨抗精子抗体（ＡｓＡｂ）和抗子宫内膜抗体（ＥｍＡｂ）与人工流产后继发不孕的关系。方法：设研究组是１１６例人工流产后不孕妇女和对照组为５１例正常育龄妇女（无人工流产和自然流产史），用酶联免疫吸附法（ＥＬＩＳＡ）分别测定血清和宫颈粘液中的ＡｓＡｂ和血清中的ＥｍＡｂ。结果：研究组中ＡｓＡｂ阳性率和ＥｍＡｂ阳性率分别是：血清中ＡｓＡｂ为３５３４％，宫颈粘液中ＡｓＡｂ为４１３８％，血清中ＥｍＡｂ为３６２１％，均高于对照组，差异有显著性意义（Ｐ＜００１）。结论：ＡｓＡｂ和ＥｍＡｂ是人工流产后引起女性免疫性不孕的重要因素。因此，对人工流产后继发性不孕者免疫因素的诊断和治疗是必要的。 Objective: To investigate the relationship between anti-sperm antibody (AsAb) and anti-endometrial antibody (EmAb) and secondary infertility after induced abortion. Methods: One hundred and sixty-one cases of post-abortion infertility women and 51 cases of normal women of reproductive age (without induced abortion and spontaneous abortion) were enrolled in the study group. Serum and cervical mucus were measured by enzyme-linked immunosorbent assay (ELISA) AsAb and serum EmAb. Results: The positive rate of AsAb and the positive rate of EmAb were 3534% in serum, 4138% in cervical mucus and 3621% in serum, which were higher than those in control group Significant (P <001). Conclusion: AsAb and EmAb are the important factors that cause female infertility after induced abortion. Therefore, it is necessary to diagnose and treat the immune factors of secondary infertility after induced abortion.