论文部分内容阅读
目的:比较昂丹司琼与甲氧氯普胺预防胆囊术后呕吐的疗效和安全性。方法:244例患者随机分为A组82例,诱导期静注昂丹司琼4 mg,之后每隔8 h静滴4 mg,连用3 d;B组82例,诱导期肌注甲氧氯普胺10 mg,之后每隔8 h肌注10 mg,连用3 d;C组80例,不使用止吐剂。三组麻醉方法相同。记录病人术后72 h内呕吐情况及10 d内其他并发症及副反应。结果:A组呕吐率0％,B组呕吐率28．05％,C组呕吐率92．50％。A组与B组比较有统计学差异(P<0．01)。结论:昂丹司琼预防胆囊术后呕吐高效、安全。
Objective: To compare the efficacy and safety of ondansetron and metoclopramide in preventing vomiting after gallbladder surgery. Methods: A total of 244 patients were randomly divided into group A (n = 82), induction of ondansetron 4 mg, intravenous infusion of 4 mg every 8 h for 3 days, group B (n = 82) 10 mg of amines, and then every 10 h intramuscular injection of 10 mg, once every 3 days; C group 80 cases, do not use antiemetic. The same three groups of anesthesia. The patient’s vomiting within 72 hours after operation and other complications and side effects within 10 days were recorded. Results: The vomiting rate in group A was 0%, the rate of vomiting in group B was 28.05%, and the rate of vomiting in group C was 92.50%. There was a significant difference between group A and group B (P <0.01). Conclusion: Ondansetron can prevent vomiting efficiently and safely after gallbladder surgery.