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尽管目前不断有新的抗真菌药物用于临床,但侵袭性真菌病患者预后仍然不佳,这多是因为缺乏早期快速诊断真菌病的方法。早期诊断与真菌病患者预后息息相关。传统的真菌病诊断方法包括临床样本直接镜检、培养和组织病理学诊断。一些新的诊断方法包括抗原检测、分子生物学和基于蛋白质组学的诊断方法也逐渐被用于真菌病的诊断。这些新的方法显著提高了疾病的早期诊断水平。
Although new antifungal agents are currently being used clinically, the prognosis of patients with invasive mycosis remains poor, mostly due to a lack of early rapid diagnosis of fungal diseases. Early diagnosis and fungal disease are closely related to the prognosis. Traditional methods of mycosis diagnosis include direct microscopic examination of clinical specimens, culture and histopathological diagnosis. Some new diagnostic methods, including antigen detection, molecular biology and proteomics-based diagnostic methods are gradually being used for the diagnosis of fungal diseases. These new methods significantly improve the early diagnosis of the disease.