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从水朝阳旋覆花(Inula helianthus-aquatica)地上部分分离得到24个化合物,经波谱数据分析分别鉴定为aromaticin(1),8-epi-helenalin(2),bigelovin(3),2,3-dihydroaromaticin(4),carpesiolin(5),ergolide(6),inuchinenolide C(7),6α-acetoxy-isoinuviscolide(8),8-epi-inuviscolide(9),inuchinenolide B(10),tomentosin(11),11α,13-dihydrotomentosin(12),inuchinenolide A(13),4H-tomentosin(14),11β,13-dihydro-4H-tomentosin(15),11-epi-sundiversifolide(16),sundiversifolide(17),8,9,10-三羟基百里香酚(18),10-羟基-8,9-双氧亚异丙基百里香酚(19),8,10-二羟基-9-异丁酰百里香酚(20),8-羟基-9,10-二异丁酰百里香酚(21),8-羟基-9-异丁酰-10-(2-甲基丁酰)百里香酚(22),8,9-环氧-9,10-二异丁酰百里香酚(23)和8,9-环氧-3-异丁酰-10-(2-甲基丁酰)百里香酚(24)。除了化合物1~6外,其他化合物均为首次从该植物中分离得到。
Twenty-four compounds were isolated from aerial parts of Inula helianthus-aquatica and identified as aromaticin (1), 8-epi-helenalin (2), bigelovin (3), 2,3- dihydroaromaticin (4), carpesiolin (5), ergolide (6), inuchinenolide C (7), 6α- acetoxy- isoinuviscolide (8), 8- epi-inuviscolide (9), inuchinenolide B (10), tomentosin (13), 4H-tomentosin (14), 11β, 13-dihydro-4H-tomentosin (15), 11- epi-sundiversifolide (16), sundiversifolide Trihydroxythymol (18), 10-hydroxy-8,9-dioxyisopropylidenethymol (19), 8,10-dihydroxy-9- isobutyrylthymol (20) , 8-hydroxy-9,10-diisobutyryl thymol (21), 8-hydroxy-9- isobutyryl-10- (2- methylbutyryl) thymol (22) Oxo-9,10-diisobutyryl thymol (23) and 8,9-epoxy-3-isobutyryl-10- (2-methylbutyryl) thymol (24). All the compounds except for compounds 1 ~ 6 were isolated from this plant for the first time.