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吡喹酮是一种对人体5种主要血吸虫病(曼氏、埃及、湄公、间插与日本血吸虫病)都非常有效的药物。全球已对1亿多例血吸虫感染者及有疫水接触史的可能感染者用吡喹酮进行了治疗,积累了极为丰富的经验。该文概述自吡喹酮问世以来国外用吡喹酮治疗几种血吸虫病的效果、副反应及吡喹酮在几个主要流行国家(埃及、巴西、老挝、印度尼西亚、菲律宾)防治规划中的应用。
Praziquantel is a very potent drug for five of the major human schistosomiasis (Man’s, Egyptian, Mekong, Interplanetary and Schistosoma japonicum). The world has more than 100 million cases of schistosomiasis and infectious water contact history may be infected with praziquantel for treatment, has accumulated a wealth of experience. This article provides an overview of the effects of several foreign schistosomiasis treatments with praziquantel since the advent of praziquantel and its application in the prevention and control of praziquantel in several major endemic countries (Egypt, Brazil, Laos, Indonesia, Philippines) .