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目的 提高胃嗜酸性肉芽肿的诊治水平及疗效。方法 回顾性分析 1988年 8月～1998年 10月我院收治经手术病理证实的胃嗜酸性肉芽肿病人 2 0例 ,并进行随访。结果 5例行部分胃切除 ,8例行大部胃切除 ,3例行次全胃切除 ,4例行根治性胃切除术 ,手术无并发症及死亡。随访经X线钡餐或纤维胃镜复查 18例 (90 % ) ,其中 7～ 9年 10例 ,4～ 6年 6例 ,1～ 3年 2例 ,均无复发 ,且未见癌变。结论 仔细询问病史 ,X线钡餐、纤维胃镜及外周血嗜酸性粒细胞计数是明确胃嗜酸性肉芽肿的重要依据。其中纤维胃镜必须在溃疡边缘作挖掘式活检深达胃粘膜下组织病理检查 ,可提高术前诊断率。手术切除是最有效的治疗方法。
Objective To improve the diagnosis and treatment of gastric eosinophilic granuloma and its efficacy. Methods A retrospective analysis of 20 patients with gastric eosinophilic granuloma confirmed by surgery in our hospital from August 1988 to October 1998 was performed and followed up. Results 5 cases underwent partial gastrectomy, 8 cases underwent radical gastrectomy, 3 cases underwent total gastrectomy, and 4 cases underwent radical gastrectomy. There were no complications and death during operation. Follow-up X-ray barium meal or fiber endoscopy in 18 cases (90%), of which 7 to 9 years in 10 cases, 4 to 6 years in 6 cases, 1 to 3 years in 2 cases, no recurrence, and no cancer. Conclusions Careful history, X-ray barium meal, fiber endoscopy and peripheral blood eosinophil count is an important basis for the identification of gastric eosinophilic granuloma. The fiber endoscopy must be in the edge of the ulcer for biopsy deep gastric mucosal histopathological examination, can improve the preoperative diagnosis rate. Surgical resection is the most effective treatment.