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目的探讨血必净注射液对三氯乙烯药疹样皮炎(DMLT)患者肿瘤坏死因子-α(TNF-α)及凝血功能的影响。方法将38例DMLT患者随机分为2组,对照组20例予常规综合治疗,治疗组18例加用血必净注射液治疗。分别检测2组治疗前后的TNF-α、凝血酶原时间(PT)、凝血酶时间(TT)、活化部分凝血活酶时间(APTT)和纤维蛋白原(FBG)。结果治疗后治疗组检测指标与对照组比较,差异有统计学意义。结论血必净注射液对DMLT患者的凝血功能有保护作用。
Objective To investigate the effect of Xuebijing injection on tumor necrosis factor-α (TNF-α) and coagulation function in patients with trichlorethylene-eruid-like dermatitis (DMLT). Methods Thirty-eight patients with DMLT were randomly divided into two groups. The control group, 20 cases were treated by conventional therapy. The treatment group, 18 cases were treated with Xuebijing injection. The levels of TNF-α, PT, TT, APTT and fibrinogen (FBG) were measured before and after treatment. Results After treatment, the treatment group test indicators compared with the control group, the difference was statistically significant. Conclusion Xuebijing Injection has a protective effect on the coagulation function of DMLT patients.