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目的：研究后路寰椎侧块螺钉联合枢椎椎板钩内固定的生物力学稳定性。方法取6例新鲜尸体颈椎标本，每具标本分别依次进行完整（正常组）、寰枢椎不稳（失稳组）、寰枢侧块螺钉联合枢椎椎弓根螺钉钉棒固定（Harms组）、寰椎侧块螺钉联合枢椎椎板钩固定（钉钩组）状态的生物力学测试，每组6个标本，将各标本装载在脊柱三维运动机上，分别施予1.5 N·m力矩，记录标本在前屈后伸、左右侧曲、左右旋转3个方向上的活动度（ROM），比较各组ROM。结果相对于正常组标本，失稳组标本在上述3个方向上的ROM显著增大；相较于正常和失稳组标本，Harms组和钉钩组的标本在上述3个方向上ROM显著减小；钉钩组与Harms组间在上述3个方向的ROM差异无统计学意义（P>0.05）。结论后路寰椎侧块螺钉联合枢椎椎板钩内固定在生物力学稳定性上与Harms固定相似，可以起到良好的固定效果。“,”Objective To research the biomechanical stability of posterior atlas lateral mass screw combined axis lamina hook for laminar fixation. Methods Six fresh human cervical specimens were treated into test models as the following order:normal (intact group),atlanto-axial instability(instable group),atlas lateral mass screw combined axis pedicle screw fixation(Harms group),atlas lateral mass screw combined axis lamina hook fixation(hook group). All the specimens were loaded in 3 dimensional spinal motion machine and forced to simulate human cervical motion in extension/flexion,left/right bending,left/right rotation directions by the moment of 1.5 N·m. The range of motion(ROM) of each motion were recorded and compared in pairs. Results Compared with the normal group,the ROMs of all specimen in the instable group were significantly increased in 3 directions. Compared with the normal and instable groups,the ROMs of Harms group/atlas lateral mass screw combined axis and hook group were significantly reduced in 3 directions. There was no significant difference in the ROMs between the 2 fixation methods in 3 directions(P>0.05). Conclusion Posterior atlas lateral mass screw combined axis lamina hook fixation has the similar biomechanical stability to atlas lateral mass screw combined axis pedicle screw fixation,and both can obtain good fixation effect.