广州番禺地区无偿献血人群HIV感染情况及人群特征分析

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目的了解近5年广州番禺地区无偿献血人群抗-HIV感染情况,分析其人群特征,为本地区HIV预防宣传及无偿献血招募工作提供参考。方法回顾分析2010-2014年本地区无偿献血人群抗-HIV筛查及确证情况,查询抗HIV-1确证阳性者档案资料,用spss19.0软件统计分析流行病学资料。结果 158 320份标本中,WB(Western Blot)确证HIV-1阳性标本有26例,近5年本地区无偿献血人群HIV感染率1.64/万(26/158 320)。各年龄组比较:χ~2=13.47,P<0.01,26例感染者均为40岁以下;不同文化程度组比较:χ~2=12.75,P<0.01,高中以下学历占92.3%(24/26);不同职业组比较:χ~2=48.31,P<0.01,其中工人组占76.9%(20/26);26例感染者中,非广州市户籍占96.15%(25/26),首次及重复献血者分别占76.9%、23.1%,有2例在CDC确证阳性后仍重复参加无偿献血,感染途径以非婚性传播为主。结论血站要继续严格HIV筛查的同时,还要从无偿献血招募工作开始把好关,结合血站信息系统对献血者尤其是低学历外来务工者进行有效的献血前健康征询,对于多次献血合格的再次献血者,也不能放松征询要求,避免有高危行为的人或者阳性病例参与无偿献血。 Objective To understand the anti-HIV infection in unpaid blood donors in Panyu, Guangzhou in the recent 5 years and analyze the characteristics of their populations so as to provide a reference for HIV prevention publicity and voluntary blood donation recruitment in this area. Methods Retrospective analysis of 2010-2014 anti-HIV screening and confirmatory confirmation of unpaid blood donors in this area, check the file of anti-HIV-1 positive, and use the software of SPSS19.0 to analyze the epidemiological data. Results Of the 158 320 samples, WB (Western Blot) confirmed HIV-1 positive samples in 26 cases. In the recent 5 years, the HIV prevalence of unpaid blood donors in this area was 1.64 / million (26/158 320). The results of different age groups showed that: χ ~ 2 = 13.47, P <0.01, all of 26 infected persons were under 40 years of age; χ ~ 2 = 12.75, P < 26%). Among different occupational groups, χ ~ 2 = 48.31, P <0.01, of which workers accounted for 76.9% (20/26). Among the 26 infected persons, non-Guangzhou residents accounted for 96.15% (25/26) And repeat blood donors accounted for 76.9% and 23.1% respectively. Two of them continued to participate in blood donation after confirmation of positive CDC. The main route of infection was non-marital transmission. Conclusions While continuing to rigorous HIV screening, blood donation should begin with taking good care off blood donation and blood bank information system to conduct effective pre-donation health consultation for blood donors, especially those with low education level. Re-donated blood donors, nor can relax the request for advice, to avoid high-risk behavior or positive cases involved in blood donation.
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