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目的研究NT-proBNP判断高龄心力衰竭急性失代偿期的预后效果。方法选择2013年10月—2014年11月漯河市第六人民医院治疗心力衰竭急性失代偿期的老年患者136例,根据NT-proBNP数值四分位数法分成Q1-Q4四组,每组各34例;随访1年根据预后结局不同分成观察组66例、对照组70例,观察组为再入院或病死,对照组为未再入院。观察所有患者的预后指标变化。结果 Q4组LVESVI、再入院率及病死率明显高于其余3组,差异有统计学意义(P<0.05);观察组患者的NT-proBNP、LVESVI明显高于对照组,差异有统计学意义(P<0.05)。结论 NT-proBNP的浓度越高,患者的再入院率及病死率越高,说明NT-proBNP可以判断心力衰竭急性失代偿期的病情及预后效果。
Objective To study the prognostic value of NT-proBNP in judging acute decompensated heart failure in elderly patients. Methods From October 2013 to November 2014, 136 cases of elderly patients with acute decompensated heart failure in the Sixth People’s Hospital of Luohe City were divided into four groups of Q1-Q4 according to the NT-proBNP numerical quartile method. Each group Each 34 cases were followed up for one year. According to the prognosis, 66 cases were divided into observation group and 70 cases in control group. The observation group was re-admitted or died and the control group was not re-admitted. All patients were observed for changes in prognostic indicators. Results The LVESVI, readmission rate and mortality in Q4 group were significantly higher than those in the other three groups (P <0.05). The NT-proBNP and LVESVI in the observation group were significantly higher than those in the control group P <0.05). Conclusion The higher the concentration of NT-proBNP, the higher the readmission rate and mortality of patients, indicating that NT-proBNP can determine the acute decompensation of heart failure and prognosis.