手性化合物的合成及其螺旋结构与光学活性的关系的研究 ,是当今有机化学发展中的前沿课题之一。本项工作以 R- ( +) - 1,1′-联 - 2 -萘酚为原料 ,在有机碱的催化下与丁二酰氯环合 ,得到联二萘酚螺环酯类衍生物。并结合已有的研究工作 ,根据 X-衍射结构 ,利用 NMR、IR、MS、UV等测试手段 ,确定出了产物的结构 The synthesis of chiral compounds and their relationship between helix structure and optical activity are one of the frontier topics in the development of organic chemistry today. In this work, R- (+) - 1,1’-bi-2-naphthol was used as a starting material to cyclize succinyl chlorides under the catalysis of organic bases to obtain binaphthol spirocyclic derivatives. Combined with the existing research work, the structure of the product was confirmed by X-ray diffraction, NMR, IR, MS and UV.