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目的:评价复方利多卡因乳膏在多种皮肤性病浅表麻醉的效果和安全性。方法:采用多中心、自体双盲对照的方法,对60例次物理治疗患者的不同皮疹处分别涂抹复方利多卡因乳膏(1号组)和恩纳乳膏(2号组)。比较两组的临床疗效和安全性。结果:1号组显效率为48.33%,总有效率为96.67%,2号组显效率为53.33%,总有效率为98.33%,两组间比较,显效率和总有效率差异均无显著性(P>0.05)。两组药物不良反应均轻微,安全性高。结论:复方利多卡因乳膏作为表面麻醉剂,麻醉效果显著、安全、无明显不良反应,值得临床使用。
OBJECTIVE: To evaluate the efficacy and safety of compound lidocaine cream in superficial anesthesia of multiple dermatological diseases. Methods: Multi-center and self-double-blind control method was used to apply compound lidocaine cream (group 1) and ena cream (group 2) to different skin rash of 60 cases of physical therapy patients. The clinical efficacy and safety of the two groups were compared. Results: The effective rate was 48.33% in group 1, the total effective rate was 96.67%, the effective rate in group 2 was 53.33% and the total effective rate was 98.33%. There was no significant difference between the two groups in apparent effective rate and total effective rate (P> 0.05). Two groups of adverse drug reactions are mild, high safety. Conclusion: The compound lidocaine cream as a topical anesthetic, anesthesia effect was significant, safe, no obvious adverse reactions, is worth clinical use.