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目的探讨硫酸舒喘灵对中重度卵巢过度刺激综合征(Ovarian hyperstimulation syndrome,OHSS)的治疗作用。方法临床选取40例中重度卵巢过度刺激综合征患者,平均分为治疗组和对照组。治疗组在扩容、补液基础上给予硫酸舒喘灵治疗,对照组仅给予扩容、补液对症治疗,最后对两组疗效进行分析、评估。结果对照组20例中16例妊娠,4例流产,平均住院时间34.3天,平均症状缓解时间3周;治疗组20例中20例妊娠,0例流产,平均住院时间20.8天,平均症状缓解时间1周。两组相比有显著性差异(P<0.05)。结论硫酸舒喘灵是肾上腺素β2受体兴奋剂,在中重度OHSS治疗中可明显改善患者临床症状及预防流产,缩短住院时间,不失为一种较好的治疗药物。
Objective To investigate the therapeutic effect of Scutellarin on Ovarian hyperstimulation syndrome (OHSS). Methods 40 cases of moderate and severe ovarian hyperstimulation syndrome were selected clinically and divided into treatment group and control group. In the treatment group, Salbutamol Sulfate was given on the basis of volume expansion and rehydration. The control group was only treated with dilatation and rehydration symptomatic treatment. Finally, the curative effect of both groups was analyzed and evaluated. Results In the control group, 16 cases of pregnancy and 4 cases of miscarriage were found in 20 cases. The average length of hospital stay was 34.3 days and the mean symptom relief time was 3 weeks. In the 20 cases of treatment group, 20 cases were pregnant and 0 cases were miscarried. The average hospitalization time was 20.8 days. 1 week. There was significant difference between the two groups (P <0.05). Conclusion Scutellarin sulfate is an adrenergic β2 receptor agonist. It may improve the clinical symptoms and prevent abortion and shorten the length of hospital stay in patients with moderate-severe OHSS, which is a good therapeutic drug.