The throughput performance of modulation and coding schemes (MCS) selection with channel quality estimation errors (CQEE) is analyzed for high-speed downlink packet access (HSDPA). To reduce the loss of throughput caused by CQEE, the robust MCS selection method and adaptive MCS switching scheme are proposed. In addition, automatic repeat request (ARQ) scheme is used to improve the block error rate (BLER) performance. Simulation results show that the proposed methods decrease the throughput loss resulted from CQEE efficiently and BLER performance gets better with ARQ scheme. The throughput performance of modulation and coding schemes (MCS) selection with channel quality estimation errors (CQEE) is analyzed for high-speed downlink packet access (HSDPA). To reduce the loss of throughput caused by CQEE, the robust MCS selection method and adaptive Simulation results show that the proposed methods decrease the throughput loss resulted from CQEE efficiently and BLER performance gets better with the MCS switching scheme are proposed. ARQ scheme.