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目的:观察有剖宫产史妇女中期妊娠引产中应用米非司酮配伍米索前列醇方法的安全性与有效性。方法:选择妊娠12~20周剖宫产史孕妇40例,B超示:子宫瘢痕愈合良好,其中A组20例采用米非司酮配伍米索前列醇。B组米非司酮联合利凡诺羊膜腔穿刺方法终止妊娠。观察两组引产效果及安全性。结果:A组总产程时间明显短于B组(P<0.05),产时出血,宫颈裂伤等并发症,两组间差异无统计学意义(P>0.05)。结论:米非司酮联合米索前列醇用于愈合良好的瘢痕子宫中期妊娠安全有效。
Objective: To observe the safety and efficacy of mifepristone combined with misoprostol in induction of labor in women with a history of cesarean section. Methods: Forty pregnant women with history of cesarean delivery during 12 to 20 weeks of gestation were selected. B-mode ultrasound showed good healing of uterine scar. A group of 20 patients were treated with mifepristone and misoprostol. Group B mifepristone combined rivanol amniocentesis termination of pregnancy. Observation of two groups of induction of labor and safety. Results: The total labor duration in group A was significantly shorter than that in group B (P <0.05), bleeding at birth, and cervical laceration. There was no significant difference between the two groups (P> 0.05). Conclusions: Mifepristone combined with misoprostol is safe and effective for healing a good metaphase scar.