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目的初步探讨和总结应用Glubran2胶超选择性术前栓塞颅底脑膜瘤的疗效和安全性。方法对12例经DSA全脑血管造影证实为完全以颈外动脉供血或以颈外动脉供血为主的颅底脑膜瘤,应用Glubran2胶通过微导管超选择术前栓塞肿瘤,栓塞后7~9d行手术切除肿瘤。结果栓塞后肿瘤染色完全消失5例,大部分消失7例,无栓塞相关并发症。肿瘤全切除9例,大部切除3例,术中出血少,手术时间在2~5h,平均3.5h,术后病人均恢复良好。结论 Glubran2胶超选择性术前栓塞颅底脑膜瘤是一种安全、有效的方法,有助于减少手术切除肿瘤过程中失血、缩短手术时间、降低手术难度、提高肿瘤的全切率、减少手术并发症。
Objective To investigate and summarize the efficacy and safety of Glubran2 gel preoperatively for embolization of skull base meningiomas. Methods Twenty-two patients with cranial base meningiomas, which were mainly from the external carotid artery or from the external carotid artery, were confirmed by DSA. Cerebellar meningiomas were mainly selected by Glubran2 gel through microcatheter. Seventy-nine days after embolization Surgical removal of the tumor. Results After embolization, the tumors completely disappeared in 5 cases, most of them disappeared in 7 cases without embolism related complications. Total tumor resection in 9 cases, most of the resection in 3 cases, less bleeding, surgery time in 2 ~ 5h, an average of 3.5h, postoperative patients were recovered well. Conclusion Glubran2 glue preoperative selective embolization of skull base meningioma is a safe and effective method to reduce the blood loss during surgical resection of the tumor, shorten the operation time, reduce the operation difficulty, improve the rate of tumor resection, reduce the operation complication.