采用溶栓疗法治疗 32例急性脑梗死 (6h以内 )患者 ,并与 32例常规方法治疗的急性脑梗死患者 (6h以内 )进行对照 ,观察两组疗法对IL 1β、IL 6及TNF α的影响 ,并对其疗效进行分析。结果显示 ,溶栓组IL 1β、IL 6及TNF α在溶栓后 2h及6h明显下降 ,与治疗效果及预后显著相关。与对照组比较 ,其欧洲卒中评分 (ESS )和 3个月后的Bathal指数明显改善。提示溶栓组治疗的近、远期效果均明显好于常规治疗组 Thirty-two patients with acute cerebral infarction (within 6 hours) were treated with thrombolytic therapy, and compared with 32 patients with acute cerebral infarction (within 6 hours) treated by conventional method. The effects of two therapies on IL-1β, IL-6 and TNFα , And analyze its efficacy. The results showed that the levels of IL-1β, IL-6 and TNF-α in thrombolytic group decreased significantly at 2h and 6h after thrombolysis, which were significantly correlated with the treatment outcome and prognosis. Compared with the control group, the European stroke score (ESS) and Bathal index after 3 months significantly improved. Tip thrombolytic group treatment of near and long-term results were significantly better than the conventional treatment group