我们曾用药抑空斑法复筛获得了小蘖胺等五种抗流感病毒药物。现以小白鼠为流感实验动物模型用粗制小蘖胺进行治疗,以确定其在体内的效果。材料和方法一、药物 1.粗制小蘖胺粉剂批号7802粗制小蘖胺粉剂系以三颗针提取黄连硷后的废液中粗提制得,批号7811样品系由十大功劳提取黄连硷后的废液中粗提制得,二者均由贵阳制药厂供给。 2.粗制小蘖胺药液取粗制小蘖胺1克,加蒸馏水100毫升,用NHCI调pH至3左右,加热溶解、 We have used drugs to suppress screening and obtained five anti-influenza virus drugs such as Berbamine. The mice were treated with crude Berbamine to determine the effect in vivo. Materials and Methods 1. Drug 1. Crude berbamine powder No. 7802 Crude berbamine powder was prepared by extracting the waste liquid from Huanglian Cockroach with three needles. Lot 7811 was extracted from Coptis chinensis by batch The crude liquid was extracted from the waste afterwards and both were supplied by Guiyang Pharmaceutical Factory. 2. Crude beryllium amine solution Take crude berylamine 1 gram, add distilled water 100 ml, adjust the pH to about 3 with NHCI, heat and dissolve,