我们在大骨节病患病率58.1%,病情活跃指数56.8,病情严重程度指数69.8属相对活跃重病区的达拉滨农场,曾进行过12个月投服亚硒酸钠防治效果观察。其结果:亚硒酸钠组好转率90%(18/20),对照组(服淀粉片)15.8%(3/19),趋于自然好转。两组经统计学处理有高度显著差异(x~2=21.59,p<0.005)。此后1989年4月～1990年4月开展维生素C 与亚硒酸钠防治大骨节病效果对比观察。对象和方法:选择经X 线确诊的6～13岁 We observed 58.1% prevalence of Kashin-Beck disease, active disease index 56.8, and disease severity index 69.8 in darabinan farms with relatively active disease areas. We conducted 12-month surveillance of the efficacy of sodium selenite. As a result, the improvement rate of sodium selenite group was 90% (18/20) and that of the control group (starch tablet) was 15.8% (3/19), which tended to naturally improve. The two groups were statistically significant (x ~ 2 = 21.59, p <0.005). Since 1989 April ~ April 1990 to carry out vitamin C and sodium selenite prevention and treatment of Kashin-Beck disease effect comparison. Subjects and methods: choose to be diagnosed by X-ray 6 to 13 years old