恶性肿瘤具有普遍的止血功能异常,10～30%的病人可发生血栓并发症,而出血经常是DIC的结果。利用放射性同位素标记纤维蛋白原测定,肿瘤病人术后下肢静脉血栓形成高达50～55%。恶性肿瘤死亡的病人中,45～55%可见肺动脉血栓栓塞性病变。在各种肿瘤中,血栓形成的发生率以胰癌为最高,其次为肺癌、胃癌、结肠癌和女性生殖器官的恶性肿瘤等。 Malignant tumors have a common hemostatic dysfunction, thrombotic complications in 10 to 30% of patients, and bleeding is often the result of DIC. The use of radioactive isotope labeled fibrinogen determination of tumor patients postoperative venous thrombosis up to 50 ~ 55%. Among the patients who died of malignant tumor, 45% -55% showed pulmonary thromboembolic disease. In various tumors, the incidence of thrombosis is the highest pancreatic cancer, followed by lung cancer, stomach cancer, colon cancer and female genital mutilation.