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目的探讨多原发癌(multiple primary malignancies,MPMs)患者的临床特点、诊断、治疗及预后。方法对1993年5月至2009年5月治疗的73例MPMs患者的临床资料进行回顾性分析。结果 73例多原发癌全部为双重癌,发生率为0.57%。同时性MPMs 25例,异时性MPMs 48例。首发癌发病高低顺序为消化系统、头颈部、乳腺、肺。重复癌的发病高低顺序为消化系统、肺、头颈部、泌尿、生殖系统、乳腺。结论提高对MPMs的认识,做到早发现、早诊断及积极治疗,可延长生存期,改善预后。
Objective To investigate the clinical features, diagnosis, treatment and prognosis of patients with multiple primary malignancies (MPMs). Methods The clinical data of 73 patients with MPM treated from May 1993 to May 2009 were retrospectively analyzed. Results 73 cases of multiple primary cancer all double cancer, the incidence was 0.57%. Simultaneous MPMs in 25 cases, chronotropic MPMs in 48 cases. The incidence of cancer incidence order of the digestive system, head and neck, breast, lungs. The order of the incidence of repeat cancer is digestive system, lung, head and neck, urinary system, reproductive system and mammary gland. CONCLUSIONS: To raise awareness of MPMs so that early detection, early diagnosis and aggressive treatment can prolong survival and improve prognosis.